• Ago Driven Non Coding Rnas

Ago Driven Non Coding Rnas

Ago Driven Non Coding Rnas

( from 245 reviews )
  • Author
    Bibekanand Mallick
  • Publisher
    Academic Press
  • Publication date
    20 January 2019

eBook includes PDF, ePub, Mobi, Tuebl and Kindle version
FREE registration for 1 month TRIAL Account. DOWNLOAD as many books as you like (Personal use). CANCEL the membership at ANY TIME if not satisfied. Join Over 150.000 Happy Readers.

All secure, we guaranted 100% privacy and your information is safe

Loading activity ...

Loading...

Book Description

The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health.

This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases.

  • Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications
  • Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets
  • Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells
  • Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis
  • Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy

Book Detail

  • Book Title

    Ago Driven Non Coding Rnas

  • Author

    Bibekanand Mallick

  • Date Published

    20 January 2019

  • Publisher

    Academic Press

  • Pages

    387 pages

  • ISBN

    9780128156704

Book Reviews

  • User294785

    4.5 starsThanks to EUROBOOK and my winning this book, I was able to get an advanced look into Bibekanand Mallick's newest book Ago Driven Non Coding Rnas. Having been very much spooked by his Ago Driven Non Coding Rnas, I was quite happy to once again enter the world of "spookdom" and read this story. Teenagers are quite impressionable. They often believe a lot of things and try to grab onto concepts and ideas that at times seems quite out of the norm. They often make ready partners, easily led, and make decisions that oftenti.

  • User392855

    A short but w lovely book for fans of both authors, but also a lot of insight into freedom of speach, creativity and the importance of libraries. Some words to take to heart, some words to live by, some words to get (more) liberated in the pursuit of artistic endeavours. Definitely a good thing to read. You don't know it yet, but it's likely you need this book.

  • User345211

    I'm pretty sure Bibekanand Mallick books just exist to capture and devour your entire SOUL AND IMAGINATION. I just went on such a wild adventure omg, I feel actually drained. Like this duology has totally filled my creative well. I am heart eyes and my heart so so full and !!!! my emotions are just !!! which is exactly how a professionally reviewer would summarise a book.

  • User95812

    I know a lot of us were expecting Ago Driven Non Coding Rnas to be good, but I have to say, this book actually exceeded my expectations. I have a lump in my throat and I can't stop thinking about it. I usually spend time making detailed notes while reading a book but, at one point, I opened Notes on my computer just to type "oh fucking god, this is so good".

  • User192812

    DANG THIS BOOK IS GOOD. Full review coming, just need to collect my thoughts. I LOVED this - absolutely worth adding to your summer TBR!!.

  • Mary

    not going to lie, i'm feeling PRETTY special for receiving an advance copy of this(okay yes i haven't read Ago Driven Non Coding Rnas but still)

lEAVE a rEPLY

© euro-book.net 2021

DISCLAIMER: "We cannot guarantee that every book is in the library. But if You are still not sure with the service, you can choose FREE Trial service. You can cancel anytime. You can also find customer support email or phone in the next page and ask more details about availability of this book. By accessing this site you agree to be bound by our Privacy Policy.

1208 Members Online